Search Result

Results for "

anti-obesity activity

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Aldose Reductase (1) AP-1 (1) Apoptosis (2) Autophagy (2) Bacterial (6) c-Myc (1) Casein Kinase (1) Caspase (1) COX (1) Drug Metabolite (1) Endogenous Metabolite (3) ERK (1) Estrogen Receptor/ERR (1) FOXO (1) GSK-3 (1) HIF/HIF Prolyl-Hydroxylase (1) Influenza Virus (2) Interleukin Related (1) Isotope-Labeled Compounds (1) MCHR1 (GPR24) (1) Mitochondrial Metabolism (1) NF-κB (1) NO Synthase (1) PARP (2) Phosphatase (1) PI3K (2) PPAR (4) Reactive Oxygen Species (2) VEGFR (1) β-catenin (1)
By Research Areas:	Cancer (13) Cardiovascular Disease (2) Infection (6) Inflammation/Immunology (8) Metabolic Disease (21) Neurological Disease (3)

By Targets:

Akt (1)

Aldose Reductase (1)

AP-1 (1)

Apoptosis (2)

Autophagy (2)

Bacterial (6)

c-Myc (1)

Casein Kinase (1)

Caspase (1)

COX (1)

Drug Metabolite (1)

Endogenous Metabolite (3)

ERK (1)

Estrogen Receptor/ERR (1)

FOXO (1)

GSK-3 (1)

HIF/HIF Prolyl-Hydroxylase (1)

Influenza Virus (2)

Interleukin Related (1)

Isotope-Labeled Compounds (1)

MCHR1 (GPR24) (1)

Mitochondrial Metabolism (1)

NF-κB (1)

NO Synthase (1)

PARP (2)

Phosphatase (1)

PI3K (2)

PPAR (4)

Reactive Oxygen Species (2)

VEGFR (1)

β-catenin (1)

By Research Areas:

Cancer (13)

Cardiovascular Disease (2)

Infection (6)

Inflammation/Immunology (8)

Metabolic Disease (21)

Neurological Disease (3)

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Fat Mass and Obesity-associated Protein (FTO)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W005130

2,4,6-Trihydroxybenzaldehyde	NF-κB	Metabolic Disease
2,4,6-Trihydroxybenzaldehyde is an orally active NF-ĸB inhibitor. 2,4,6-Trihydroxybenzaldehyde shows anti-tumor activity, anti-cancer cell proliferative activity and anti-obesity activity .

HY-N0055

Chlorogenic acid Maximum Cited Publications 14 Publications Verification 3-O-Caffeoylquinic acid; Heriguard; NSC-407296	HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species Bacterial Influenza Virus Endogenous Metabolite	Infection Inflammation/Immunology Cancer
Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb. It is an orally active antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension compound .

HY-135190

(-)-Cedrene 1 Publications Verification α-cedrene	Bacterial	Infection Metabolic Disease Cancer
(-)-Cedrene (α-cedrene) is a sesquiterpene constituent of cedarwood oils, with anti-leukemic, antimicrobial and anti-obesity activities .

HY-Y0078

Cinnamyl Alcohol 1 Publications Verification	PPAR	Metabolic Disease
Cinnamyl Alcohol is an active component from chestnut flower, inhibits increased PPARγ expression, with anti-obesity activity .

HY-N0114

Evodiamine 5+ Cited Publications (+)-Evodiamine; d-Evodiamine	Others	Cancer
Evodiamine is an alkaloid isolated from the fruit of Evodia rutaecarpa Bentham with diverse biological activities including anti-inflammatory, anti-obesity, and antitumor.

HY-112920

TM-25659

Others Metabolic Disease

TM-25659 is a transcriptional co-activator with PDZ-binding motif (TAZ) modulator. Anti-osteoporotic and anti-obesity activities .

TM-25659	Others	Metabolic Disease
TM-25659 is a transcriptional co-activator with PDZ-binding motif (TAZ) modulator. Anti-osteoporotic and anti-obesity activities .

HY-N5117

Kaempferol 3-sophoroside-7-glucoside	Others	Metabolic Disease
Kaempferol 3-sophoroside-7-glucoside is a bioactive component in roasted Lycium chinense leaves with anti-obesity activity .

HY-N8359

Questinol

Others Metabolic Disease

Questinol is a palmitic acid that can be isolated from Talaromyces stipitatus. Questinol has signi?cant anti-obesity activity in zebra?sh larvae .

Questinol	Others	Metabolic Disease
Questinol is a palmitic acid that can be isolated from Talaromyces stipitatus. Questinol has signi?cant anti-obesity activity in zebra?sh larvae .

HY-B2188

S-Methyl-L-cysteine L-S-Methylcysteine	Reactive Oxygen Species	Neurological Disease Metabolic Disease
S-Methyl-L-cysteine is a natural product that acts as a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA), with antioxidative, neuroprotective, and anti-obesity activities.

HY-N6871

Abietic acid	Bacterial	Infection Metabolic Disease Inflammation/Immunology Cancer
Abietic acid, a diterpene isolated from Colophony, possesses antiproliferative, antibacterial, and anti-obesity properties. Abietic acid inhibits lipoxygenase activity for allergy treatment .

HY-N11773

Gancaonin L	PPAR	Metabolic Disease
Gancaonin L is an isoflavone, that can be isolated from Glycyrrhiza glabra roots. Gancaonin L exhibits significant PPAR-γ ligand-binding activity. Gancaonin L can be used for anti-diabetes and anti-obesity research .

HY-N8362

1-Isomangostin	Others	Metabolic Disease
1-Isomangostin is an inhibitor of pancreatic lipase. 1-Isomangostin inhibits porcine pancreatic lipase with an IC₅₀ of 34.5 μM. 1-Isomangostin has anti-obesity activity .

HY-N2302

Fucoxanthin 5+ Cited Publications all-trans-Fucoxanthin	Bacterial PPAR c-Myc NO Synthase Caspase ERK	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Fucoxanthin (all-trans-Fucoxanthin) is a marine carotenoid and shows anti-obesity, anti-diabetic, anti-oxidant, anti-inflammatory and anticancer activities .

HY-14471

Cetilistat ATL-962	Others	Metabolic Disease
Cetilistat (ATL-962), an inhibitor of pancreatic lipase, acts as an effective anti-obesity agent. Cetilistat inhibits rat and human pancreatic lipase activity with IC₅₀s of 54.8 nM, and 5.95 nM, respectively .

HY-P3586

HKPao Hunter-killer peptide ao; Prohibitin-targeting peptide 1; prohibitin-TP01; Adipotide	Apoptosis	Cancer
HKPao (Hunter-killer peptide ao) is a biologically active peptide. HKPao (Hunter-killer peptide ao) has anti-obesity and anti-tumor pro-apoptotic activity to cause release of cytochrome c from vesicles .

HY-136124

Cetilistat impurity 1	Drug Metabolite	Others
Cetilistat impurity 1 is an impurity of Cetilistat. Cetilistat, an inhibitor of pancreatic lipase, acts as an effective anti-obesity agent. Cetilistat inhibits rat and human pancreatic lipase activity with IC₅₀s of 54.8 nM, and 5.95 nM, respectively .

HY-N1186

Tachioside
Tachioside inhibits nitric oxide production in lipopolysaccharide (HY-D1056)-stimulated RAW 264.7 cells with IC₅₀ value of 12.14 μM. Tachioside has anti-obesity, antioxidant and α-glucosidase inhibitory activities .

HY-N1867

trans-Cinnamyl alcohol
trans-Cinnamyl alcohol is a trans-isomer of Cinnamyl alcohol. Cinnamyl Alcohol is an active component from chestnut flower, inhibits increased PPARγ expression, with anti-obesity activity. trans-Cinnamyl alcohol, belongs to the class of organic compounds known as cinnamyl alcohols, is a primary metabolite .

HY-N0828

Pterostilbene 5 Publications Verification	Autophagy	Inflammation/Immunology Cancer
Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium . Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties . Pterostilbene blocks ROS production , also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide .

HY-N4103

Fucosterol	PARP Endogenous Metabolite	Metabolic Disease Cancer
Fucosterol is a sterol isolated from algae, seaweed or diatoms. Fucosterol exhibits various biological activities, including antioxidant, anti-adipogenic, blood cholesterol reducing, anti-diabetic and anti-cancer activities . Fucosterol regulates adipogenesis via inhibition of PPARα and C/EBPα expression and can be used for anti-obesity agents development research .

HY-120327

KY-226 1 Publications Verification	Phosphatase	Neurological Disease Metabolic Disease
KY-226 is a potent, selective, orally active and allosteric protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC₅₀ of 0.25 μM, and without PPARγ agonist activity. KY-226 exerts anti-diabetic and anti-obesity effects by enhancing insulin and leptin signaling, respectively. KY-226 also protects neurons from cerebral ischemic injury .

HY-117843

Ppc-1	Mitochondrial Metabolism Interleukin Related Bacterial	Infection Metabolic Disease Inflammation/Immunology
Ppc-1 is a mitochondrial uncoupler. Ppc-1 enhances mitochondrial oxygen consumption without adverse effects on ATP production. Ppc-1 is a cell-permeate interleukin-2 (IL-2) inhibitor. Ppc-1 inhibits the Gram-negative periodontopathogen *Porphyromonas gingivalis. Ppc-1 has anti-obesity, antibacterial and anti-inflammatory activities* .

HY-N2692

6,8-Diprenylgenistein	Others	Cancer
6,8-Diprenylgenistein is an isoflavone compound isolated from Cudrania tricuspidata. 6,8-Diprenylgenistein has antimicrobial and anti-obesity activity. 6,8-Diprenylgenistein inhibits the proliferation, migration and tubular formation of HLMEC induced by recombinant human vascular endothelial growth factor-A. 6,8-Diprenylgenistein can be used to study new therapeutic drugs for the prevention and treatment of oral cancer metastasis .

HY-N4103R

Fucosterol (Standard)	PARP Endogenous Metabolite	Metabolic Disease Cancer
Fucosterol (Standard) is the analytical standard of Fucosterol. This product is intended for research and analytical applications. Fucosterol is a sterol isolated from algae, seaweed or diatoms.?Fucosterol exhibits various biological activities, including antioxidant, anti-adipogenic, blood cholesterol reducing, anti-diabetic and anti-cancer activities . Fucosterol regulates adipogenesis via inhibition of?PPARα?and?C/EBPα?expression and can be used for anti-obesity agents development research .

HY-N0055S

Chlorogenic acid-13C3 3-O-Caffeoylquinic acid-₁₃C³; Heriguard-₁₃C³; NSC-407296-₁₃C³	Isotope-Labeled Compounds	Cancer
Chlorogenic acid- ¹³C₃ (Heriguard- ¹³C₃; NSC-407296- ¹³C₃) is ¹³C- and ¹⁵N-labeled Chlorogenic acid (HY-N0055). Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb.. It plays several important and therapeutic roles such as antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension .

HY-N3716

Dehydroglyasperin D	Aldose Reductase COX	Metabolic Disease Inflammation/Immunology
Dehydroglyasperin D inhibits rat and human Aldose Reductase (AR) (IC₅₀: 62.4 μM and 176.2 μM respectively). Dehydroglyasperin D has anti-obesity, antioxidant effects. Dehydroglyasperin D shows anti-inflammatory activity by inhibiting COX-2 expression and the MLK3 signaling pathway. Dehydroglyasperin D also inhibits melanin synthesis. Dehydroglyasperin D is a prenylated flavonoid that can be isolated from Glycyrrhiza uralensi .

HY-N4226

1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid	AP-1	Inflammation/Immunology Cancer
1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid is from Cordyceps bassiana, which is one of Cordyceps species with anti-oxidative, anti-cancer, anti-inflammatory, anti-diabetic, anti-obesity, anti-angiogenic, and anti-nociceptive activities. 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid targets to block AP-1-mediated luciferase activity, implying it has an anti-inflammatory function .

HY-N3127

Orobol	Casein Kinase PI3K VEGFR	Metabolic Disease
Orobol is one of the major soy isoflavones and has various pharmacological activities, including anti-skin-aging and anti-obesity effects. Orobol inhibits CK1ε, VEGFR2, MAP4K5, MNK1, MUSK, TOPK, and TNIK (IC₅₀=1.24-4.45 μM). Orobol also inhibits PI3K isoforms (IC₅₀=3.46-5.27 μM for PI3K α/β/γ/K/δ) .

HY-N2157

Pteryxin 1 Publications Verification (+)-Pteryxin
Pteryxin, a coumarin in Peucedanum japonicum Thunb leaves, exerts antiobesity activity . Pteryxin is a potent butyrylcholinesterase (BChE) inhibitor, with an IC₅₀ of 12.96 μg/ml .

HY-120608

BMS-814580	MCHR1 (GPR24)	Metabolic Disease
BMS-814580 is an orally active, highly efficacious MCHR1 inhibitor with a K_i of 16.9 nM against hMCHR1. BMS-814580 shows antiobesity activities .

HY-15449

Kaempferide 2 Publications Verification Kaempferol 4'-O-methyl ether	Estrogen Receptor/ERR Autophagy Bacterial Influenza Virus Apoptosis PI3K Akt GSK-3 FOXO β-catenin	Infection Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Kaempferide is an orally active flavonol isolated from Hippophae rhamnoides L. Kaempferide has anticancer, anti-inflammatory, antioxidant, antidiabetic, antiobesity, antihypertensive, and neuroprotective activities. Kaempferide induces apoptosis. Kaempferide promotes osteogenesis through antioxidants and can be used in osteoporosis research .

HY-100277

Mifobate 1 Publications Verification SR-202	PPAR	Metabolic Disease
Mifobate (SR-202) is a potent and specific PPARγ antagonist. Mifobate (SR-202) selectively inhibits Thiazolidinedione (TZD)-induced PPARγ transcriptional activity (IC₅₀=140 μM). Mifobate (SR-202) does not affect basal or ligand-stimulated transcriptional activity of PPARα, PPARβ, or the farnesoid X receptor (FXR). Mifobate (SR-202) shows antiobesity and antidiabetic effects .

HKPao Hunter-killer peptide ao; Prohibitin-targeting peptide 1; prohibitin-TP01; Adipotide	Apoptosis	Cancer
HKPao (Hunter-killer peptide ao) is a biologically active peptide. HKPao (Hunter-killer peptide ao) has anti-obesity and anti-tumor pro-apoptotic activity to cause release of cytochrome c from vesicles .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W005130

2,4,6-Trihydroxybenzaldehyde	Monophenols Animals Phenols	NF-κB
2,4,6-Trihydroxybenzaldehyde is an orally active NF-ĸB inhibitor. 2,4,6-Trihydroxybenzaldehyde shows anti-tumor activity, anti-cancer cell proliferative activity and anti-obesity activity .

HY-N0055

Chlorogenic acid Maximum Cited Publications 14 Publications Verification 3-O-Caffeoylquinic acid; Heriguard; NSC-407296	Structural Classification Caprifoliaceae Classification of Application Fields Anti-aging Lonicera japonica Thunb. Source classification Plants Endogenous metabolite Infection Human Gut Microbiota Metabolites Microorganisms Simple Phenylpropanols Phenols Polyphenols Phenylpropanoids Inflammation/Immunology Disease Research Fields Cancer	HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species Bacterial Influenza Virus Endogenous Metabolite
Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb. It is an orally active antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension compound .

HY-135190

(-)-Cedrene 1 Publications Verification α-cedrene	Infection Structural Classification Cedrus deodara (Roxburgh) G. Don Classification of Application Fields Pinaceae Terpenoids Sesquiterpenes Source classification Metabolic Disease Plants Disease Research Fields	Bacterial
(-)-Cedrene (α-cedrene) is a sesquiterpene constituent of cedarwood oils, with anti-leukemic, antimicrobial and anti-obesity activities .

HY-Y0078

Cinnamyl Alcohol 1 Publications Verification	Structural Classification Classification of Application Fields Simple Phenylpropanols Source classification Castanea mollissima Bl. Metabolic Disease Phenylpropanoids Plants Fagaceae Disease Research Fields	PPAR
Cinnamyl Alcohol is an active component from chestnut flower, inhibits increased PPARγ expression, with anti-obesity activity .

HY-N0114

Evodiamine 5+ Cited Publications (+)-Evodiamine; d-Evodiamine	Alkaloids Piperidine Alkaloids Structural Classification Classification of Application Fields Source classification Evodia rutaecarpa (Juss.) Benth. Rutaceae Plants Disease Research Fields Indole Alkaloids Cancer	Others
Evodiamine is an alkaloid isolated from the fruit of Evodia rutaecarpa Bentham with diverse biological activities including anti-inflammatory, anti-obesity, and antitumor.

HY-N5117

Kaempferol 3-sophoroside-7-glucoside	Flavonols Flavonoids Classification of Application Fields Sauropus spatulifolius Beille Source classification Phenols Polyphenols Metabolic Disease Euphorbiaceae Plants Disease Research Fields	Others
Kaempferol 3-sophoroside-7-glucoside is a bioactive component in roasted Lycium chinense leaves with anti-obesity activity .

HY-N8359

Questinol	Quinones Structural Classification Microorganisms Anthraquinones Source classification	Others
Questinol is a palmitic acid that can be isolated from Talaromyces stipitatus. Questinol has signi?cant anti-obesity activity in zebra?sh larvae .

HY-B2188

S-Methyl-L-cysteine L-S-Methylcysteine	Structural Classification other families Ketones, Aldehydes, Acids Source classification Plants	Reactive Oxygen Species
S-Methyl-L-cysteine is a natural product that acts as a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA), with antioxidative, neuroprotective, and anti-obesity activities.

HY-N6871

Abietic acid	Infection Structural Classification Colophony Classification of Application Fields Pinaceae Ketones, Aldehydes, Acids Metabolic Disease Plants Inflammation/Immunology Disease Research Fields	Bacterial
Abietic acid, a diterpene isolated from Colophony, possesses antiproliferative, antibacterial, and anti-obesity properties. Abietic acid inhibits lipoxygenase activity for allergy treatment .

HY-N11773

Gancaonin L	Structural Classification Flavonoids Flavones Leguminosae Source classification Plants Glycyrrhiza uralensis Fisch.	PPAR
Gancaonin L is an isoflavone, that can be isolated from Glycyrrhiza glabra roots. Gancaonin L exhibits significant PPAR-γ ligand-binding activity. Gancaonin L can be used for anti-diabetes and anti-obesity research .

HY-N8362

1-Isomangostin	Structural Classification Natural Products Source classification Guttiferae Garcinia mangostana Linn. Plants	Others
1-Isomangostin is an inhibitor of pancreatic lipase. 1-Isomangostin inhibits porcine pancreatic lipase with an IC₅₀ of 34.5 μM. 1-Isomangostin has anti-obesity activity .

HY-N2302

Fucoxanthin 5+ Cited Publications all-trans-Fucoxanthin	Structural Classification Natural Products Classification of Application Fields Anti-aging Marine natural products Source classification Whitening Agent Metabolic Disease Plants Food Research other families Sunscreen Marine algae Pigments Cosmetic Research Inflammation/Immunology Disease Research Fields Cancer	Bacterial PPAR c-Myc NO Synthase Caspase ERK
Fucoxanthin (all-trans-Fucoxanthin) is a marine carotenoid and shows anti-obesity, anti-diabetic, anti-oxidant, anti-inflammatory and anticancer activities .

HY-N0828

Pterostilbene 5 Publications Verification	Structural Classification Monophenols other families Stilbenes Classification of Application Fields Source classification Phenols Plants Inflammation/Immunology Disease Research Fields	Autophagy
Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium . Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties . Pterostilbene blocks ROS production , also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide .

HY-N4103

Fucosterol	Structural Classification other families Classification of Application Fields Source classification Metabolic Disease Plants Endogenous metabolite Disease Research Fields Steroids	PARP Endogenous Metabolite
Fucosterol is a sterol isolated from algae, seaweed or diatoms. Fucosterol exhibits various biological activities, including antioxidant, anti-adipogenic, blood cholesterol reducing, anti-diabetic and anti-cancer activities . Fucosterol regulates adipogenesis via inhibition of PPARα and C/EBPα expression and can be used for anti-obesity agents development research .

HY-N2692

6,8-Diprenylgenistein	Structural Classification Flavonoids Leguminosae Source classification Phenols Polyphenols Plants Derris taiwaniana (Hayata) Z. Q. Song Isoflavones	Others
6,8-Diprenylgenistein is an isoflavone compound isolated from Cudrania tricuspidata. 6,8-Diprenylgenistein has antimicrobial and anti-obesity activity. 6,8-Diprenylgenistein inhibits the proliferation, migration and tubular formation of HLMEC induced by recombinant human vascular endothelial growth factor-A. 6,8-Diprenylgenistein can be used to study new therapeutic drugs for the prevention and treatment of oral cancer metastasis .

HY-N4103R

Fucosterol (Standard)	Structural Classification other families Classification of Application Fields Source classification Metabolic Disease Plants Endogenous metabolite Disease Research Fields Steroids	PARP Endogenous Metabolite
Fucosterol (Standard) is the analytical standard of Fucosterol. This product is intended for research and analytical applications. Fucosterol is a sterol isolated from algae, seaweed or diatoms.?Fucosterol exhibits various biological activities, including antioxidant, anti-adipogenic, blood cholesterol reducing, anti-diabetic and anti-cancer activities . Fucosterol regulates adipogenesis via inhibition of?PPARα?and?C/EBPα?expression and can be used for anti-obesity agents development research .

HY-N3716

Dehydroglyasperin D	Structural Classification Leguminosae Source classification Phenols Polyphenols Plants Glycyrrhiza uralensis Fisch.	Aldose Reductase COX
Dehydroglyasperin D inhibits rat and human Aldose Reductase (AR) (IC₅₀: 62.4 μM and 176.2 μM respectively). Dehydroglyasperin D has anti-obesity, antioxidant effects. Dehydroglyasperin D shows anti-inflammatory activity by inhibiting COX-2 expression and the MLK3 signaling pathway. Dehydroglyasperin D also inhibits melanin synthesis. Dehydroglyasperin D is a prenylated flavonoid that can be isolated from Glycyrrhiza uralensi .

HY-N4226

1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid	other families Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Plants Disease Research Fields Cancer	AP-1
1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid is from Cordyceps bassiana, which is one of Cordyceps species with anti-oxidative, anti-cancer, anti-inflammatory, anti-diabetic, anti-obesity, anti-angiogenic, and anti-nociceptive activities. 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid targets to block AP-1-mediated luciferase activity, implying it has an anti-inflammatory function .

HY-N3127

Orobol	Flavonoids Classification of Application Fields Leguminosae Glycine max (L.) merr Source classification Phenols Polyphenols Metabolic Disease Plants Disease Research Fields Isoflavones	Casein Kinase PI3K VEGFR
Orobol is one of the major soy isoflavones and has various pharmacological activities, including anti-skin-aging and anti-obesity effects. Orobol inhibits CK1ε, VEGFR2, MAP4K5, MNK1, MUSK, TOPK, and TNIK (IC₅₀=1.24-4.45 μM). Orobol also inhibits PI3K isoforms (IC₅₀=3.46-5.27 μM for PI3K α/β/γ/K/δ) .

HY-15449

Kaempferide 2 Publications Verification Kaempferol 4'-O-methyl ether	Infection Flavonols Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Alpinia officinarum Hance Plants Disease Research Fields Zingiberaceae	Estrogen Receptor/ERR Autophagy Bacterial Influenza Virus Apoptosis PI3K Akt GSK-3 FOXO β-catenin
Kaempferide is an orally active flavonol isolated from Hippophae rhamnoides L. Kaempferide has anticancer, anti-inflammatory, antioxidant, antidiabetic, antiobesity, antihypertensive, and neuroprotective activities. Kaempferide induces apoptosis. Kaempferide promotes osteogenesis through antioxidants and can be used in osteoporosis research .

Cat. No.	Product Name	Chemical Structure

HY-N0055S

Chlorogenic acid-13C3

Chlorogenic acid- ¹³C₃ (Heriguard- ¹³C₃; NSC-407296- ¹³C₃) is ¹³C- and ¹⁵N-labeled Chlorogenic acid (HY-N0055). Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb.. It plays several important and therapeutic roles such as antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension .

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anti-obesity activity

Inhibitors & Agonists

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Isotope-Labeled Compounds

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